The Protective Role of Microglial PPARα in Diabetic Retinal Neurodegeneration and Neurovascular Dysfunction

The Protective Role of Microglial PPARα in Diabetic Retinal Neurodegeneration and Neurovascular Dysfunction

Microglial activation and subsequent pathological neuroinflammation contribute to diabetic retinopathy (DR). However, the underlying mechanisms of microgliosis, and means to effectively suppress pathological microgliosis, remain incompletely understood. Peroxisome proliferator-activated receptor alp...

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Bibliographic Details
Main Authors: Tian Yuan, Lijie Dong, Elizabeth A. Pearsall, Kelu Zhou, Rui Cheng, Jian-Xing Ma
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
diabetic retinopathy
microglial metabolism
mitochondrion
glycolysis
inflammation
neurodegeneration
Online Access:https://www.mdpi.com/2073-4409/11/23/3869

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https://www.mdpi.com/2073-4409/11/23/3869

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