Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A<sub>2</sub>γ in Phospholipid Remodeling

Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A<sub>2</sub>γ in Phospholipid Remodeling

Availability of free arachidonic acid (AA) constitutes a rate limiting factor for cellular eicosanoid synthesis. AA distributes differentially across membrane phospholipids, which is largely due to the action of coenzyme A-independent transacylase (CoA-IT), an enzyme that moves the fatty acid primar...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Patricia Lebrero, Alma M. Astudillo, Julio M. Rubio, Lidia Fernández-Caballero, George Kokotos, María A. Balboa, Jesús Balsinde
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2019-07-01
Schriftenreihe:Cells
Schlagworte:
arachidonic acid
eicosanoids
inflammation
phospholipid remodeling
phospholipase A<sub>2</sub>
monocytes/macrophages
Online Zugang:https://www.mdpi.com/2073-4409/8/8/799

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https://www.mdpi.com/2073-4409/8/8/799

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