A self‐propagating, barcoded transposon system for the dynamic rewiring of genomic networks

Abstract In bacteria, natural transposon mobilization can drive adaptive genomic rearrangements. Here, we build on this capability and develop an inducible, self‐propagating transposon platform for continuous genome‐wide mutagenesis and the dynamic rewiring of gene networks in bacteria. We first use...

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Bibliographic Details
Main Authors: Max A English, Miguel A Alcantar, James J Collins
Format: Article
Language:English
Published: Springer Nature 2023-03-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.202211398