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Exploring the conformational dynamics and thermodynamics of EGFR S768I and G719X + S768I mutations in non-small cell lung cancer: An in silico approaches

Exploring the conformational dynamics and thermodynamics of EGFR S768I and G719X + S768I mutations in non-small cell lung cancer: An in silico approaches

Bibliographic Details
Main Authors: Wang Jun-Ling, Liu Ming-Sheng, Fu Yu-Dong, Kan Qiang-Bo, Li Chun-Yan, Ma Rong, Fang Zhe-Wei, Liu Hong-Xia, Li Meng-Xian, Lv Jia-Ling, Sang Peng, Zhang Chao, Li Hong-Wei
Format: Article
Language:English
Published: De Gruyter 2023-11-01
Series:Open Life Sciences
Subjects:
epidermal growth factor receptor g719x and s768i mutations
non-small cell lung cancer
molecular dynamics simulation
conformation
free energy landscape
Online Access:https://doi.org/10.1515/biol-2022-0768
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https://doi.org/10.1515/biol-2022-0768

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