CREB5 promotes the proliferation and self-renewal ability of glioma stem cells

Abstract Glioblastoma multiforme (GBM) is the most fatal form of brain cancer in humans, with a dismal prognosis and a median overall survival rate of less than 15 months upon diagnosis. Glioma stem cells (GSCs), have recently been identified as key contributors in both tumor initiation and therapeu...

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Bibliographic Details
Main Authors: Hyun-Jin Kim, Hye-Min Jeon, Don Carlo Batara, Seongsoo Lee, Suk Jun Lee, Jinlong Yin, Sang-Ik Park, Minha Park, Jong Bae Seo, Jinik Hwang, Young Joon Oh, Sung-Suk Suh, Sung-Hak Kim
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01873-z