Methylome Profiling of PD-L1-Expressing Glioblastomas Shows Enrichment of Post-Transcriptional and RNA-Associated Gene Regulation

Methylome Profiling of PD-L1-Expressing Glioblastomas Shows Enrichment of Post-Transcriptional and RNA-Associated Gene Regulation

Glioblastomas are the most frequent primary brain tumors in adults. They show highly malignant behavior and devastating outcomes. Since there are still no targeted therapies available, median survival remains in the range of 12 to 15 months for glioblastoma patients. Programmed Cell Death Ligand 1 (...

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Bibliographic Details
Main Authors: Georg Hutarew, Dorothee Hölzl, Tanja Schiefer, Celina K. Langwieder, Beate Alinger-Scharinger, Hans U. Schlicker, Christoph Schwartz, Karl Sotlar, Theo F. J. Kraus
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
glioblastoma
epigenetic profiling
methylome
programmed cell death ligand 1
precision medicine
Online Access:https://www.mdpi.com/2072-6694/14/21/5375

Internet

https://www.mdpi.com/2072-6694/14/21/5375

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