Research Progress in Preparation of Bioactive Peptides from Milk by Microbial Fermentation

Animal milk has become the major source of bioactive peptides due to its high contents of proteins and essential amino acids, high yield and good stability. Bioactive peptides are encrypted and inactive in the parental proteins, so they must be released to show their biological activity. Depending o...

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Main Author: LI Siyi, JIANG Yutong, TUO Yanfeng, WU Xiaomeng, MU Guangqing, JIANG Shujuan
Format: Article
Language:English
Published: China Food Publishing Company 2023-11-01
Series:Shipin Kexue
Subjects:
Online Access:https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-21-035.pdf
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author LI Siyi, JIANG Yutong, TUO Yanfeng, WU Xiaomeng, MU Guangqing, JIANG Shujuan
author_facet LI Siyi, JIANG Yutong, TUO Yanfeng, WU Xiaomeng, MU Guangqing, JIANG Shujuan
author_sort LI Siyi, JIANG Yutong, TUO Yanfeng, WU Xiaomeng, MU Guangqing, JIANG Shujuan
collection DOAJ
description Animal milk has become the major source of bioactive peptides due to its high contents of proteins and essential amino acids, high yield and good stability. Bioactive peptides are encrypted and inactive in the parental proteins, so they must be released to show their biological activity. Depending on their amino acid compositions, sizes, sequences, and physicochemical properties, bioactive peptides can exert angiotensin converting enzyme (ACE) inhibitory, antioxidant, antibacterial, antithrombotic, or immunomodulatory effects. Microbial fermentation is an effective method to prepare bioactive peptides. In this paper, the research progress in the preparation of milk derived bioactive peptides by microbial fermentation is reviewed, the diversity of bioactive peptides produced by different microbial proteases is clarified, and future trends for the preparation of bioactive peptides by microbial fermentation are discussed. This review is expected to provide a theoretical basis for the development and utilization of milk derived bioactive peptides in the future.
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spelling doaj.art-32db4a72f5e24006832743160fb2ec5a2023-12-26T06:45:07ZengChina Food Publishing CompanyShipin Kexue1002-66302023-11-01442131232910.7506/spkx1002-6630-20221104-047Research Progress in Preparation of Bioactive Peptides from Milk by Microbial FermentationLI Siyi, JIANG Yutong, TUO Yanfeng, WU Xiaomeng, MU Guangqing, JIANG Shujuan0(School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China)Animal milk has become the major source of bioactive peptides due to its high contents of proteins and essential amino acids, high yield and good stability. Bioactive peptides are encrypted and inactive in the parental proteins, so they must be released to show their biological activity. Depending on their amino acid compositions, sizes, sequences, and physicochemical properties, bioactive peptides can exert angiotensin converting enzyme (ACE) inhibitory, antioxidant, antibacterial, antithrombotic, or immunomodulatory effects. Microbial fermentation is an effective method to prepare bioactive peptides. In this paper, the research progress in the preparation of milk derived bioactive peptides by microbial fermentation is reviewed, the diversity of bioactive peptides produced by different microbial proteases is clarified, and future trends for the preparation of bioactive peptides by microbial fermentation are discussed. This review is expected to provide a theoretical basis for the development and utilization of milk derived bioactive peptides in the future.https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-21-035.pdfmilk; bioactive peptide; microbial fermentation
spellingShingle LI Siyi, JIANG Yutong, TUO Yanfeng, WU Xiaomeng, MU Guangqing, JIANG Shujuan
Research Progress in Preparation of Bioactive Peptides from Milk by Microbial Fermentation
Shipin Kexue
milk; bioactive peptide; microbial fermentation
title Research Progress in Preparation of Bioactive Peptides from Milk by Microbial Fermentation
title_full Research Progress in Preparation of Bioactive Peptides from Milk by Microbial Fermentation
title_fullStr Research Progress in Preparation of Bioactive Peptides from Milk by Microbial Fermentation
title_full_unstemmed Research Progress in Preparation of Bioactive Peptides from Milk by Microbial Fermentation
title_short Research Progress in Preparation of Bioactive Peptides from Milk by Microbial Fermentation
title_sort research progress in preparation of bioactive peptides from milk by microbial fermentation
topic milk; bioactive peptide; microbial fermentation
url https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-21-035.pdf
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