Herpes Simplex Virus 1-Induced Ferroptosis Contributes to Viral Encephalitis

Herpes Simplex Virus 1-Induced Ferroptosis Contributes to Viral Encephalitis

ABSTRACT Herpes simplex virus 1 (HSV-1) is a DNA virus belonging to the family Herpesviridae. HSV-1 infection causes severe neurological disease in the central nervous system (CNS), including encephalitis. Ferroptosis is a nonapoptotic form of programmed cell death that contributes to different neur...

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Bibliographic Details
Main Authors: Xi-Qiu Xu, Tongran Xu, Wenting Ji, Chong Wang, Yujie Ren, Xiaobei Xiong, Xi Zhou, Shu-Hai Lin, Yi Xu, Yang Qiu
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:mBio
Subjects:
ferroptosis
HSV-1
Nrf2-Keap1
PTGS2/PGE2
viral encephalitis
Online Access:https://journals.asm.org/doi/10.1128/mbio.02370-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02370-22

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