Investigating a new generation of ribozymes in order to target HCV.

For a long time nucleic acid-based approaches directed towards controlling the propagation of Hepatitis C Virus (HCV) have been considered to possess high potential. Towards this end, ribozymes (i.e. RNA enzymes) that specifically recognize and subsequently catalyze the cleavage of their RNA substra...

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Bibliographic Details
Main Authors: Michel V Lévesque, Dominique Lévesque, Francis P Brière, Jean-Pierre Perreault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2835756?pdf=render