MicroRNA-18a regulates the metastatic properties of oral squamous cell carcinoma cells via HIF-1α expression

MicroRNA-18a regulates the metastatic properties of oral squamous cell carcinoma cells via HIF-1α expression

Abstract Background Rapid metastasis of oral squamous cell carcinoma (OSCC) is associated with a poor prognosis and a high mortality rate. However, the molecular mechanisms underlying OSCC metastasis have not been fully elucidated. Although deregulated expression of microRNA (miRNA) has a crucial ro...

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Bibliographic Details
Main Authors: Shihyun Kim, Suyeon Park, Ji-Hyeon Oh, Sang Shin Lee, Yoon Lee, Jongho Choi
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Oral Health
Subjects:
Oral squamous cell carcinoma
MicroRNA
Hypoxia
HIF-1α
Migration
Invasion
Online Access:https://doi.org/10.1186/s12903-022-02425-6

Internet

https://doi.org/10.1186/s12903-022-02425-6

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