Transcriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder

Transcriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder

Abstract Sarcopenia, the progressive decline in skeletal muscle mass and function, is observed in various conditions, including cancer and aging. The complex molecular biology of sarcopenia has posed challenges for the development of FDA-approved medications, which have mainly focused on dietary sup...

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Bibliographic Details
Main Authors: Min Hak Lee, Bada Lee, Se Eun Park, Ga Eul Yang, Seungwoo Cheon, Dae Hoon Lee, Sukyeong Kang, Ye Ji Sun, Yongjin Kim, Dong-sub Jung, Wonwoo Kim, Jihoon Kang, Yi Rang Kim, Jin Woo Choi
Format: Article
Language:English
Published: Nature Publishing Group 2024-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01189-z

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https://doi.org/10.1038/s12276-024-01189-z

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