Impact of administered amount of peptide on tumor dosimetry at the first cycle of peptide receptor radionuclide therapy (PRRT) in relation to total tumor somatostatin receptor expression

Impact of administered amount of peptide on tumor dosimetry at the first cycle of peptide receptor radionuclide therapy (PRRT) in relation to total tumor somatostatin receptor expression

Abstract Background The accumulation of 177Lu-DOTATATE might be influenced by the amount of administered peptide in relation to the tumor somatostatin receptor expression. The effect of the administered peptide mass on the resulting absorbed dose in tumors and normal organs has not previously been a...

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Bibliographic Details
Main Authors: Ulrika Jahn, Ulrike Garske-Román, Mattias Sandström, Mark Lubberink, Anders Sundin
Format: Article
Language:English
Published: SpringerOpen 2023-05-01
Series:EJNMMI Research
Subjects:
Peptide
SUV
Small intestinal NET
Pancreatic NET
Somatostatin receptor
PRRT
Online Access:https://doi.org/10.1186/s13550-023-00997-0

Internet

https://doi.org/10.1186/s13550-023-00997-0

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