Role of the protease-activated receptor-2 (PAR2) in the exacerbation of house dust mite-induced murine allergic lung disease by multi-walled carbon nanotubes

Role of the protease-activated receptor-2 (PAR2) in the exacerbation of house dust mite-induced murine allergic lung disease by multi-walled carbon nanotubes

Abstract Background Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) has been reported to exert strong pro-inflammatory and pro-fibrotic adjuvant effects in mouse models of allergic lung disease. However, the molecular mechanisms through which MWCNTs exacerbate allergen-induced lung dise...

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Bibliographic Details
Main Authors: Ho Young Lee, Dorothy J. You, Alexia Taylor-Just, Logan J. Tisch, Ryan D. Bartone, Hannah M. Atkins, Lauren M. Ralph, Silvio Antoniak, James C. Bonner
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Particle and Fibre Toxicology
Subjects:
Carbon nanotubes
Allergens
Protease-activated receptor 2
Lung
Inflammation
Fibrosis
Online Access:https://doi.org/10.1186/s12989-023-00538-6

Internet

https://doi.org/10.1186/s12989-023-00538-6

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