Notch signaling regulates strain-mediated phenotypic switching of vascular smooth muscle cells

Notch signaling regulates strain-mediated phenotypic switching of vascular smooth muscle cells

Mechanical stimuli experienced by vascular smooth muscle cells (VSMCs) and mechanosensitive Notch signaling are important regulators of vascular growth and remodeling. However, the interplay between mechanical cues and Notch signaling, and its contribution to regulate the VSMC phenotype are still un...

Full description

Bibliographic Details
Main Authors: Cansu Karakaya, Mark C. van Turnhout, Valery L. Visser, Tommaso Ristori, Carlijn V. C. Bouten, Cecilia M. Sahlgren, Sandra Loerakker
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Notch signaling
vascular smooth muscle cells
phenotype
mechanosensitive
strain
stretch quantification
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.910503/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.910503/full

Similar Items