Synthetic β-sheets mimicking fibrillar and oligomeric structures for evaluation of spectral X-ray scattering technique for biomarker quantification

Abstract Background Archetypical cross-β spines sharpen the boundary between functional and pathological proteins including β-amyloid, tau, α-synuclein and transthyretin are linked to many debilitating human neurodegenerative and non-neurodegenerative amyloidoses. An increased focus on development o...

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Bibliographic Details
Main Authors: Karthika Suresh, Eshan Dahal, Aldo Badano
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-024-01208-6