Effects of rosmarinic acid on DNA integrity and H19 differentially methylated region methylation levels in human sperm preserved by freeze-drying

Objective: To investigate the effects of rosmarinic acid (RA) on the DNA integrity and methylation levels of the H19 differentially methylated region (DMR) of freeze-dried human sperm after 1 week and 6 months of storage at 4°C. Methods: Semen samples from 15 healthy normospermic donors were used in...

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Bibliographic Details
Main Authors: Yi-Yu Wang, Wei-Jie Zhu
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2021-01-01
Series:Reproductive and Developmental Medicine
Subjects:
Online Access:http://www.repdevmed.org/article.asp?issn=2096-2924;year=2021;volume=5;issue=1;spage=9;epage=14;aulast=Wang