Anti-diabetic effect of loganin by inhibiting FOXO1 nuclear translocation via PI3K/Akt signaling pathway in INS-1 cell

Anti-diabetic effect of loganin by inhibiting FOXO1 nuclear translocation via PI3K/Akt signaling pathway in INS-1 cell

Objective(s): JiangTangXiaoKe (JTXK) granule, a Chinese traditional herbal formula, has been clinically used and demonstrated to be beneficial in controlling high glucose and to relieve the symptoms of  Type 2 diabetes mellitus patients for decades. In this study, we explored how loganin, one of the...

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Bibliographic Details
Main Authors: Fang-Fang Mo, Hai-Xia Liu, Yi Zhang, Jing Hua, Dan-Dan Zhao, Tian An, Dong-Wei Zhang, Tian Tian, Sihua Gao
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Akt pathway
Factor forkhead box O1-(FOXO1)
INS-1 cells
Loganin
Pancreatic β-cell
Online Access:http://ijbms.mums.ac.ir/article_12189_0aada324bcc5a71a6841ea2e8adec17b.pdf

Internet

http://ijbms.mums.ac.ir/article_12189_0aada324bcc5a71a6841ea2e8adec17b.pdf

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