Activation of Dendritic Cells by the Novel Toll-Like Receptor 3 Agonist RGC100

Toll-like receptor (TLR) 3 agonists emerged as attractive candidates for vaccination strategies against tumors and pathogens. An important mechanism of action of such agonists is based on the activation of TLR3-expressing dendritic cells (DCs), which display a unique capacity to induce and stimulate...

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Bibliographic Details
Main Authors: Kai Naumann, Rebekka Wehner, Anett Schwarze, Christiane Petzold, Marc Schmitz, Jacques Rohayem
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/283649