Generation and characterization of a genetic Parkinson’s disease-patient derived iPSC line DJ-1-delP (LCSBi008-A)

Here, we describe an induced pluripotent stem cell (iPSC) line that was derived from fibroblasts obtained from a monogenic Parkinson’s disease (PD) patient. The disease was caused by a c.634-636delGCC mutation in the PARK7 gene leading to p.158P deletion in the protein DJ-1. iPSCs were generated via...

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Bibliographic Details
Main Authors: Pauline Mencke, Ibrahim Boussaad, Gizem Önal, Anneke J.A. Kievit, Agnita J.W. Boon, Wim Mandemakers, Vincenzo Bonifati, Rejko Krüger
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122001416