Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation

Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation

Fibrogenic and inflammatory processes in the prostate are linked to the development of lower urinary tract symptoms (LUTS) in men. Our previous studies identified that osteopontin (OPN), a pro-fibrotic cytokine, is abundant in the prostate of men with LUTS, and its secretion is stimulated by inflamm...

Full description

Bibliographic Details
Main Authors: Petra Popovics, Asha Jain, Kegan O. Skalitzky, Elise Schroeder, Hannah Ruetten, Mark Cadena, Kristen S. Uchtmann, Chad M. Vezina, William A. Ricke
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
prostatic fibrosis
extracellular matrix
benign prostatic hyperplasia
lower urinary tract symptoms
chronic inflammation
Online Access:https://www.mdpi.com/1422-0067/22/22/12461

Internet

https://www.mdpi.com/1422-0067/22/22/12461

Similar Items