Top-Down Clustering for Protein Subfamily Identification
We propose a novel method for the task of protein subfamily identification; that is, finding subgroups of functionally closely related sequences within a protein family. In line with phylogenomic analysis, the method first builds a hierarchical tree using as input a multiple alignment of the protein...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-01-01
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Series: | Evolutionary Bioinformatics |
Online Access: | https://doi.org/10.4137/EBO.S11609 |