In Vivo Monitoring of Pancreatic β-Cells in a Transgenic Mouse Model

We generated a transgenic mouse model ( RIP-luc ) for the in vivo monitoring of pancreatic islet mass and function in response to metabolic disease. Using the rat insulin promoter fused to firefly luciferase, and noninvasive technology to detect luciferase activity, we tracked changes in reporter si...

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Bibliographic Details
Main Authors: Steven J. Smith, Hongbing Zhang, Anne O. Clermont, Alvin C. Powers, Dixon B. Kaufman, Anthony F. Purchio, David B. West
Format: Article
Language:English
Published: SAGE Publishing 2006-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2006.00007