Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus.

The origin of the signals that induce the differentiation of the central nervous system (CNS) is a long-standing question in vertebrate embryology. Here we show that Xenopus neural induction starts earlier than previously thought, at the blastula stage, and requires the combined activity of two dist...

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Bibliographic Details
Main Authors: Hiroki Kuroda, Oliver Wessely, E M De Robertis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC406387?pdf=render