A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis

<p>Abstract</p> <p>Background</p> <p>Hereditary Hemochromatosis(HH) is a common genetic disorder of iron overload where the large majority of patients are homozygous for one ancestral mutation in the <it>HFE </it>gene. In spite of this remarkable genetic hom...

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Bibliographic Details
Main Authors: Mascarenhas Cláudia, Krikler Samuel H, Whittington Chris, Cruz Eugénia, Lacerda Rosa, Vieira Jorge, Porto Graça
Format: Article
Language:English
Published: BMC 2008-11-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/9/97