Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins

Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins

Hemorrhage induced by snake venom metalloproteinases (SVMPs) is a complex phenomenon that involves capillary disruption and blood extravasation. HF3 (hemorrhagic factor 3) is an extremely hemorrhagic SVMP of <i>Bothrops jararaca</i> venom. Studies using proteomic approaches revealed targ...

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Bibliographic Details
Main Authors: Luciana Bertholim, Alison F. A. Chaves, Ana K. Oliveira, Milene C. Menezes, Amanda F. Asega, Alexandre K. Tashima, Andre Zelanis, Solange M. T. Serrano
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Toxins
Subjects:
<i>Bothrops jararaca</i>
HF3
human plasma
proteolysis
snake venom metalloproteinase
Online Access:https://www.mdpi.com/2072-6651/13/11/764

Internet

https://www.mdpi.com/2072-6651/13/11/764

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