Evaluating GPCR modeling and docking strategies in the era of deep learning-based protein structure prediction

Evaluating GPCR modeling and docking strategies in the era of deep learning-based protein structure prediction

While deep learning (DL) has brought a revolution in the protein structure prediction field, still an important question remains how the revolution can be transferred to advances in structure-based drug discovery. Because the lessons from the recent GPCR dock challenge were inconclusive primarily du...

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Bibliographic Details
Main Authors: Sumin Lee, Seeun Kim, Gyu Rie Lee, Sohee Kwon, Hyeonuk Woo, Chaok Seok, Hahnbeom Park
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
GPCR
Deep learning
Ligand docking
Protein structure prediction
Drug discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022005517

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http://www.sciencedirect.com/science/article/pii/S2001037022005517

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