An updated perspective on immunoglobulin replacement in chronic lymphocytic leukaemia in the era of targeted therapies

Chronic lymphocytic leukaemia (CLL) is a malignancy of clonally expanded antigen-switched, neoplastic, mature B cells. CLL is characterised by a variable degree of immunosuppression and secondary hypogammaglobulinemia. B-cell depleting therapies have historically been deployed with a proportion of p...

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Bibliographic Details
Main Authors: Sujoy Khan, David Allsup, Stefano Molica
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1135812/full