An updated perspective on immunoglobulin replacement in chronic lymphocytic leukaemia in the era of targeted therapies

An updated perspective on immunoglobulin replacement in chronic lymphocytic leukaemia in the era of targeted therapies

Chronic lymphocytic leukaemia (CLL) is a malignancy of clonally expanded antigen-switched, neoplastic, mature B cells. CLL is characterised by a variable degree of immunosuppression and secondary hypogammaglobulinemia. B-cell depleting therapies have historically been deployed with a proportion of p...

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Bibliographic Details
Main Authors:	Sujoy Khan, David Allsup, Stefano Molica
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Oncology
Subjects:	CLL hypogammaglobulinemia Ig replacement immunomodulation restoration immunity
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1135812/full

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