Tailoring selective triclosan azo-adducts: Design, synthesis, and anti-mycobacterial evaluation

A series of triclosan azo-adducts were synthesized to investigate their structure-activity relationship against Mycobacterium tuberculosis and non-tuberculous mycobacteria. The series' most potent compound was four and sixteen times more active than triclosan and rifabutin against drug-resistan...

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Bibliographic Details
Main Authors: Shekhar, Matthéo Alcaraz, Pule Seboletswe, Neha Manhas, Laurent Kremer, Parvesh Singh, Vipan Kumar
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023093908