IGF2BP2-meidated m6A modification of CSF2 reprograms MSC to promote gastric cancer progression

Abstract The interaction between tumor cells and stromal cells within the tumor microenvironment plays a critical role in cancer progression. Mesenchymal stem cells (MSCs) are important tumor stromal cells that exhibit pro-oncogenic activities when reprogrammed by the tumor. However, the precise mec...

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Bibliographic Details
Main Authors: Runbi Ji, Chenxi Wu, Jun Yao, Jiajin Xu, Jiang Lin, Hongbing Gu, Min Fu, Xiaoxin Zhang, Yongkang Li, Xu Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06163-7