The Role of GLI in the Regulation of Hepatic Epithelial–Mesenchymal Transition in Biliary Atresia
ObjectiveTo study the regulatory role of GLI1/GLI2, a nuclear transcription factor of the Sonic hedgehog (Shh) signaling pathway, in epithelial–mesenchymal transition (EMT) related to hepatic fibrosis in patients with biliary atresia (BA).MethodsThe messenger RNA (mRNA) and protein expression levels...
Main Authors: | Pu Siyu, Wang Junxiang, Wang Qi, Zhang Yimao, Jin Shuguang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-05-01
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Series: | Frontiers in Pediatrics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.861826/full |
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