Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration
<p>Abstract</p> <p>Background</p> <p>The recruitment and activation of inflammatory cells is thought to exacerbate photoreceptor death in retinal degenerative conditions such as age-related macular degeneration (AMD). We investigated the role of Müller cell-derived chem...
Main Authors: | Rutar Matt, Natoli Riccardo, Provis Jan M |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-09-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/9/1/221 |
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