Intracranial In Situ Thermosensitive Hydrogel Delivery of Temozolomide Accomplished by PLGA–PEG–PLGA Triblock Copolymer Blending for GBM Treatment

Intracranial In Situ Thermosensitive Hydrogel Delivery of Temozolomide Accomplished by PLGA–PEG–PLGA Triblock Copolymer Blending for GBM Treatment

Glioblastoma (GBM) recurrence after surgical excision has grown to be a formidable obstacle to conquer. In this research, biodegradable thermosensitive triblock copolymer, poly(D, L–lactic acid–co–glycolic acid)–b–poly(ethylene glycol)–b–poly(D, L–lactic acid–co–glycolic acid (PLGA–PEG–PLGA) was uti...

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Bibliographic Details
Main Authors: Weinan Gu, Ranran Fan, Jingnan Quan, Yi Cheng, Shanshan Wang, Hui Zhang, Aiping Zheng, Shenghan Song
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Polymers
Subjects:
glioblastoma relapse
interstitial chemotherapy
thermosensitive
PLGA–PEG–PLGA
triblock copolymer
polymer blending
Online Access:https://www.mdpi.com/2073-4360/14/16/3368

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https://www.mdpi.com/2073-4360/14/16/3368

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