Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer

Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer

Cell pyroptosis, a Gasdermin-dependent programmed cell death characterized by inflammasome, plays a complex and dynamic role in Gastric cancer (GC), a serious threat to human health. Therefore, the value of pyroptosis-related genes (PRGs) as prognostic biomarkers and therapeutic indicators for patie...

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Bibliographic Details
Main Authors: Jie Li, Tian Yu, Juan Sun, Mingwei Ma, Zicheng Zheng, Weiming Kang, Xin Ye
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Cell pyroptosis
Gastric cancer
Single-cell RNA sequencing
Immune infiltration
Prognostic signature
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000266

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http://www.sciencedirect.com/science/article/pii/S2001037024000266

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