The Pharmacological TAILS of Matrix Metalloproteinases and Their Inhibitors

The Pharmacological TAILS of Matrix Metalloproteinases and Their Inhibitors

Matrix metalloproteinases (MMPs) have been demonstrated to have both detrimental and protective functions in inflammatory diseases. Several MMP inhibitors, with the exception of Periostat<sup>®</sup>, have failed in Phase III clinical trials. As an alternative strategy, recent efforts ha...

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Manylion Llyfryddiaeth
Prif Awduron: Nabangshu Das, Colette Benko, Sean E. Gill, Antoine Dufour
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2020-12-01
Cyfres:Pharmaceuticals
Pynciau:
matrix metalloproteinases (MMPs), protease
tissue inhibitors of metalloproteinases (TIMPs), exosite
small molecule inhibitors
monoclonal antibodies
proteomics
N-terminomics
Mynediad Ar-lein:https://www.mdpi.com/1424-8247/14/1/31

Rhyngrwyd

https://www.mdpi.com/1424-8247/14/1/31

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