Constant rate of p53 tetramerization in response to DNA damage controls the p53 response

Abstract The dynamics of the tumor suppressor protein p53 have been previously investigated in single cells using fluorescently tagged p53. Such approach reports on the total abundance of p53 but does not provide a measure for functional p53. We used fluorescent protein‐fragment complementation assa...

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Bibliographic Details
Main Authors: Giorgio Gaglia, Galit Lahav
Format: Article
Language:English
Published: Springer Nature 2014-10-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20145168