Constant rate of p53 tetramerization in response to DNA damage controls the p53 response
Abstract The dynamics of the tumor suppressor protein p53 have been previously investigated in single cells using fluorescently tagged p53. Such approach reports on the total abundance of p53 but does not provide a measure for functional p53. We used fluorescent protein‐fragment complementation assa...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2014-10-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.20145168 |