Early evolution of conserved regulatory sequences associated with development in vertebrates.

Comparisons between diverse vertebrate genomes have uncovered thousands of highly conserved non-coding sequences, an increasing number of which have been shown to function as enhancers during early development. Despite their extreme conservation over 500 million years from humans to cartilaginous fi...

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Bibliographic Details
Main Authors: Gayle K McEwen, Debbie K Goode, Hugo J Parker, Adam Woolfe, Heather Callaway, Greg Elgar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2781166?pdf=render