Convection and extracellular matrix binding control interstitial transport of extracellular vesicles

Convection and extracellular matrix binding control interstitial transport of extracellular vesicles

Abstract Extracellular vesicles (EVs) influence a host of normal and pathophysiological processes in vivo. Compared to soluble mediators, EVs can traffic a wide range of proteins on their surface including extracellular matrix (ECM) binding proteins, and their large size (∼30‐150 nm) limits diffusio...

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Bibliographic Details
Main Authors: Peter A. Sariano, Rachel R. Mizenko, Venktesh S. Shirure, Abigail K. Brandt, Bryan B. Nguyen, Cem Nesiri, Bhupinder S. Shergill, Terza Brostoff, David M. Rocke, Alexander D. Borowsky, Randy P. Carney, Steven C. George
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Journal of Extracellular Vesicles
Subjects:
diffusion
exosome
gradient
integrin binding
spatial concentration
Online Access:https://doi.org/10.1002/jev2.12323

Internet

https://doi.org/10.1002/jev2.12323

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