Inhibition of Toxoplasma gondii Growth by Dihydroquinine and Its Mechanisms of Action

Inhibition of Toxoplasma gondii Growth by Dihydroquinine and Its Mechanisms of Action

Toxoplasma gondii is a zoonotic parasite that infects the brain of humans and causes cerebral toxoplasmosis. The recommended drugs for the treatment or prophylaxis of toxoplasmosis are pyrimethamine (PY) and sulfadiazine (SZ), which have serious side effects. Other drugs available for toxoplasmosis...

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Bibliographic Details
Main Authors: Aarin M. Huffman, Joseph A. Ayariga, Audrey Napier, Boakai K. Robertson, Daniel A. Abugri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
dihydroquinine
inhibition
ROS
mitochondria
infectivity
T. gondii
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.852889/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.852889/full

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