Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia

Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia

Abstract. Atypical chronic myeloid leukemia (aCML) is a BCR-ABL1-negative clonal disorder, which belongs to the myelodysplastic/myeloproliferative group. This disease is characterized by recurrent somatic mutations in SETBP1, ASXL1 and ETNK1 genes, as well as high genetic heterogeneity, thus posing...

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Main Authors: Diletta Fontana, Daniele Ramazzotti, Andrea Aroldi, Sara Redaelli, Vera Magistroni, Alessandra Pirola, Antonio Niro, Luca Massimino, Cristina Mastini, Virginia Brambilla, Silvia Bombelli, Silvia Bungaro, Alessandro Morotti, Delphine Rea, Fabio Stagno, Bruno Martino, Leonardo Campiotti, Giovanni Caocci, Emilio Usala, Michele Merli, Francesco Onida, Marco Bregni, Elena Maria Elli, Monica Fumagalli, Fabio Ciceri, Roberto A. Perego, Fabio Pagni, Luca Mologni, Rocco Piazza, Carlo Gambacorti-Passerini
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000497

Internet

http://journals.lww.com/10.1097/HS9.0000000000000497

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