17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy

17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy

Ovariectomy (OVX) conducted before the onset of natural menopause is considered to bringing forward and accelerate the process of ageing-associated neurodegeneration. However, the mechanisms underlying memory decline and other cognitive dysfunctions following OVX are unclear. Given that iron accumul...

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Bibliographic Details
Main Authors: Ying Tian, Yuan Xie, Zaixin Guo, Penghui Feng, Yang You, Qi Yu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Redox Biology
Subjects:
Surgical menopause
Ferroptosis
17β-oestradiol
Memory decline
DHODH
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172300109X

Internet

http://www.sciencedirect.com/science/article/pii/S221323172300109X

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