Paeoniflorin improves functional recovery through repressing neuroinflammation and facilitating neurogenesis in rat stroke model

Background Microglia, neuron, and vascular cells constitute a dynamic functional neurovascular unit, which exerts the crucial role in functional recovery after ischemic stroke. Paeoniflorin, the principal active component of Paeoniae Radix, has been verified to exhibit neuroprotective roles in cereb...

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Bibliographic Details
Main Authors: Hongli Tang, Leiruo Wu, Xixi Chen, Huiting Li, Baojun Huang, Zhenyang Huang, Yiyang Zheng, Liqing Zhu, Wujun Geng
Format: Article
Language:English
Published: PeerJ Inc. 2021-05-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10921.pdf