HCMV-miR-US33-5p promotes apoptosis of aortic vascular smooth muscle cells by targeting EPAS1/SLC3A2 pathway

HCMV-miR-US33-5p promotes apoptosis of aortic vascular smooth muscle cells by targeting EPAS1/SLC3A2 pathway

Abstract Background In patients with acute aortic dissection (AAD), increased vascular smooth muscle cell (VSMC) apoptosis has been found. Human cytomegalovirus (HCMV)-miR-US33-5p was significantly increased in the plasma of patients with AAD. However, the roles of miR-US33-5p in human aortic VSMC (...

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Bibliographic Details
Main Authors: Jian Dong, Shuangshuang Li, Zilin Lu, Pengcheng Du, Guangqin Liu, Mintao Li, Chao Ma, Jian Zhou, Junmin Bao
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
Acute aortic dissection
Aortic vascular smooth muscle cells
Apoptosis
miRNAs
Endothelial PAS domain protein 1
SLC3A2
Online Access:https://doi.org/10.1186/s11658-022-00340-w

Internet

https://doi.org/10.1186/s11658-022-00340-w

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