Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer.

Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer.

TMPRSS2-ERG junction oncogene is present in more than 50% of patients with prostate cancer and its expression is frequently associated with poor prognosis. Our aim is to achieve gene knockdown by siRNA TMPRSS2-ERG and then to assess the biological consequences of this inhibition. First, we designed...

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Bibliographic Details
Main Authors: Giorgia Urbinati, Hafiz Muhammad Ali, Quentin Rousseau, Hubert Chapuis, Didier Desmaële, Patrick Couvreur, Liliane Massaad-Massade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416711?pdf=render

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http://europepmc.org/articles/PMC4416711?pdf=render

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