Protective effects of wogonin on lipopolysaccharide-induced inflammation and apoptosis of lung epithelial cells and its possible mechanisms

Protective effects of wogonin on lipopolysaccharide-induced inflammation and apoptosis of lung epithelial cells and its possible mechanisms

Abstract Background Wogonin (5, 7-dihydroxy-8-methoxyflavone) is a natural di-hydroxyl flavonoid extracted from the root of Scutellaria baicalensis Georgi. This paper was intended to investigate the mechanism of action of wogonin in alleviating the inflammation and apoptosis in acute lung injury (AL...

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Bibliographic Details
Main Authors: Jinlin Ge, Huanhuan Yang, Yufeng Zeng, Yunjie Liu
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BioMedical Engineering OnLine
Subjects:
Acute lung injury
Wogonin
Inflammation
SIRT1
HMGB1 deacetylation
Online Access:https://doi.org/10.1186/s12938-021-00965-6

Internet

https://doi.org/10.1186/s12938-021-00965-6

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