Modeling early germline immunization after horizontal transfer of transposable elements reveals internal piRNA cluster heterogeneity

Modeling early germline immunization after horizontal transfer of transposable elements reveals internal piRNA cluster heterogeneity

Abstract Background A fraction of all genomes is composed of transposable elements (TEs) whose mobility needs to be carefully controlled. In gonads, TE activity is repressed by PIWI-interacting RNAs (piRNAs), a class of small RNAs synthesized by heterochromatic loci enriched in TE fragments, called...

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Bibliographic Details
Main Authors: Amna Asif-Laidin, Karine Casier, Zoheir Ziriat, Antoine Boivin, Elise Viodé, Valérie Delmarre, Stéphane Ronsseray, Clément Carré, Laure Teysset
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Biology
Subjects:
Transposable elements
piRNA clusters
PIWI-interacting RNA
Subtelomeres
Drosophila
Horizontal transfer
Online Access:https://doi.org/10.1186/s12915-023-01616-z

Internet

https://doi.org/10.1186/s12915-023-01616-z

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