Sequence-structure-function relationships in the microbial protein universe

Sequence-structure-function relationships in the microbial protein universe

Abstract For the past half-century, structural biologists relied on the notion that similar protein sequences give rise to similar structures and functions. While this assumption has driven research to explore certain parts of the protein universe, it disregards spaces that don’t rely on this assump...

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Bibliographic Details
Main Authors: Julia Koehler Leman, Pawel Szczerbiak, P. Douglas Renfrew, Vladimir Gligorijevic, Daniel Berenberg, Tommi Vatanen, Bryn C. Taylor, Chris Chandler, Stefan Janssen, Andras Pataki, Nick Carriero, Ian Fisk, Ramnik J. Xavier, Rob Knight, Richard Bonneau, Tomasz Kosciolek
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37896-w

Internet

https://doi.org/10.1038/s41467-023-37896-w

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