The effect of DNA-binding proteins on insertion sequence element transposition upstream of the bgl operon in Escherichia coli

The effect of DNA-binding proteins on insertion sequence element transposition upstream of the bgl operon in Escherichia coli

The bglGFB operon in Escherichia coli K-12 strain BW25113, encoding the proteins necessary for the uptake and metabolism of β-glucosides, is normally not expressed. Insertion of either IS1 or IS5 upstream of the bgl promoter activates expression of the operon only when the cell is starving in the pr...

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Bibliographic Details
Main Authors: Peter W. Kopkowski, Zhongge Zhang, Milton H. Saier
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Microbiology
Subjects:
IS element
insertional mutation
adaptive mutation
Crp
IHF
DNA-binding protein
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1388522/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2024.1388522/full

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