Non-Canonical Amino Acids as Building Blocks for Peptidomimetics: Structure, Function, and Applications

Non-Canonical Amino Acids as Building Blocks for Peptidomimetics: Structure, Function, and Applications

This review provides a fresh overview of non-canonical amino acids and their applications in the design of peptidomimetics. Non-canonical amino acids appear widely distributed in nature and are known to enhance the stability of specific secondary structures and/or biological function. Contrary to th...

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Bibliographic Details
Main Authors: Tarsila G. Castro, Manuel Melle-Franco, Cristina E. A. Sousa, Artur Cavaco-Paulo, João C. Marcos
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomolecules
Subjects:
non-canonical amino acids
side-chain modifications
backbone modifications
peptidomimetics
foldamers
structure-function relationship
Online Access:https://www.mdpi.com/2218-273X/13/6/981

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https://www.mdpi.com/2218-273X/13/6/981

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