IL28B polymorphism cannot predict response to interferon alpha treatment in patients with melanoma.

BACKGROUND:Recent genome-wide association studies revealed the rs12979860 single nucleotide polymorphism (SNP) of the IL28B gene (CC genotype) to be the strongest pre-therapeutic predictor of therapy response to interferon alpha in patients with chronic hepatitis C infection. The favorable CC genoty...

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Bibliographic Details
Main Authors: Martin Probst, Christoph Hoeller, Peter Ferenci, Albert F Staettermayer, Sandra Beinhardt, Hubert Pehamberger, Harald Kittler, Katharina Grabmeier-Pfistershammer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4229256?pdf=render